The Use Of Therapeutic Nanoparticles As Drug Delivery...

Nanotechnology is an expanding research field that involves the engineering of functional systems at the molecular level and is capable of transforming the view of some pharmaceutical companies in the foreseeable future. This review article discusses the current treatment techniques on nanoparticles as carrier systems for the delivery of anticancer drug molecules. A plethora of nanoparticle drug delivery formulations have been tested for their target specificity. The drug delivery system of nanoparticles is designed in such a way that they are independent of their environments and selective at a biological site. Some key features of drug delivery systems include parameters such as molecular weight, pH, particulate size, ionic strength and†¦show more content†¦Advantages in nanoparticle drug delivery include improved pharmacokinetics, reduced side effects and longer circulation half-lives.1 In addition, nanoparticles may be able to achieve improved delivery of sparingly water soluble compounds by delivering a small particle size to increase the total surface area of the drugs allowing faster dissolution in the blood stream. These benefits have made therapeutic nanoparticles a promising candidate to replace conventional chemotherapeutic protocol, eliminating toxic agents and dose-limiting side effects which pose a threat to healthy tissues. The purpose of this review article on nanoparticles is to show the promise of delivering a range of molecules to desired sites in the body to treat cancer. In addition, it highlights numerous areas of opportunity where nanotechnology could enable innovative classes of therapeutics. Multifunctional HER2-Antibody Polymeric Nanocarrier Drug Delivery Stem for Breast Cancer. Nanotechnology based therapeutic approaches are promising for multifunctional treatment of cancer and it has potential in enhancing the drug delivery system of anticancer drug to tumor tissue by minimizing the toxicology in healthy tissue. Breast cancer is the leading type of cancer in women. Tamoxifen is an antagonist of the estrogen receptor in breast tissue and is the anti-estrogen therapy for hormone receptor positive